Here's an interesting article from HBR that illustrates once again how things we take for granted influence our perception and decision making.
I might have argued that it was really all the biscuits, gravy and fried chicken that weighs down the south, but as it turns out, being at the bottom of the map has its advantages (yes, beyond the biscuits).
It seems that we tend to find things that are "down" more accessible and easier to deal with than things that are "up." And that seems to extend to the map, where we find traveling south easier than traveling north (all of you who grew up in the 70s, please stop shouting "but, north is up!")
Think about that next time you give directions to something you claim is really easy to get to, or when you're heading down home for some (yum!) biscuits.